The storm prompted a tornado warning near Woodruff and Moore where there is considerable damage in the Green Pond area.
The National Weather Service says at least nine possible tornadoes were spotted across the region, CBS News correspondent DeMarco Morgan reports.
The watch is in effect until 9 p.m., but actual threat for the Rock Hill area looks to be before 6 p.m.
The National Weather Service is calling for a line of thunderstorms to strike northwestern Moore County.
Officials with Spartanburg Regional say they have received eight storm-related injuries, but majority are minor.
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People took to social media to post photos and videos of the widespread destruction left behind by the storms. Then the storm moved north-northeast heading toward the city of Spartanburg.
Eight minor injuries were reported, but no deaths.
Another team will focus on the damage stretching north across the NC Foothills. Flooding was also reported in Asheville and Boone, according to the AP.
At the Hickory Regional Airport, small planes were flipped over and hangars were crumpled, possibly by a tornado.
The storms closed two state parks in North Carolina, spokeswoman Katie Hall said. At Stone Mountain State Park in Alleghany and Wilkes counties, down trees prompted officials to close the park.