The 32-year-old Spain forward has not played for over a year and he was once told by a doctor that he would be lucky to walk again after repeated problems in his ankle.
Santi Cazorla has revealed that he almost had to have his foot amputated due to an infection during his injury lay-off.
Marca say when Cazorla was initially seeing English doctors about the issue, the outlook was bleak, with the Arsenal player revealing advice from one medic: "If you get to walk again with your son in the garden, be satisfied, they told me".
Arsenal midfielder Santi Cazorla hopes to return to action in January after undergoing eight operations in the space of a year following severe right ankle injury complications.
Cazorla is said to be targeting a return in January. He lost eight centimetres of his achilles and was told there was a risk of a blood infection that could have spread and resulted in the amputation of his right leg.
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"He saw that I had a tremendous infection, that I had damaged part of the bone and damaged the Achilles tendon", Cazorla explained.
The Spanish worldwide contracted a serious blood infection during the treatment process, which had it not been treated, may have resulted in the loss of his foot.
He is continuing his rehabilitation at the clinic of Spain physio Juan Carlos Herraez in the small city of Salamanca, two hours west of Madrid.
"He noted that I had a awful infection, that I had damaged part of the calcaneus bone which ate into the Achilles tendon, there was eight centimetres missing". Everything that I have gone through has not been as simple an injury as people have believed.
Since his arrival from Malaga in 2012, Santi Cazorla has become a mainstay in the Arsenal teamsheet, but injuries have limited his appearances. "Nobody trusted me but I do, I still do, although the pain keeps me cautious".