City have now lost their last three matches - twice against Liverpool and the defeat to Manchester United in the derby - but Guardiola said they should be proud of what they have achieved over the season with his side needing just two victories to wrap up the Premier League title.
Premier League leaders City completely dominated the first half as they attempted to salvage the tie after last week's 3-0 loss at Anfield.
"I said he was wrong", said Guardiola when asked about his dismissal. In fact, their best moment came just before half-time when Alex Oxlade Chamberlain, hardly noticeable in the game up to that point, drove at the City defence and nearly got in. When you say: 'Pep, what you have done in Barcelona or Bayern Munich, is it possible to do that without those big players?' - it's impossible, so be calm.
Speaking to BT Sport after the game, Salah reflected: "I think the [his] goal was at a good time for us because they were pressing very high and had many chances, so in the beginning we struggled a little bit because they scored in the first two minutes".
Of course Klopp said "Yes you are sitting too deep because you are not pushing up".
City protested strongly, arguing the ball towards Sane had come off Liverpool's James Milner.
"The referee is a special guy, he likes to be different".
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Yet after Bernardo Silva hit the post in the 40th minute and Leroy Sane had an effort ruled out for a disputed offside two minutes later, City had just the solitary goal to show for their first-half exertions. That's why he sent me off.
Georginio Wijnaldum played Mane in on goal and although the Senegal forward slipped as Ederson came out to meet him, Salah was on hand to clip over the keeper for his 39th goal of the season. It would have been different to go in 2-0. "The goal from Gabriel Jesus in Anfield was a goal, not offside".
Liverpool head coach Jurgen Klopp feels the club deserves to be in the last English team in the UEFA Champions League progressing to the semi-final stage at the expense of 'the best team in the world'.
"To recover three goals is not easy".
Guardiola defended a policy that has seen him spend some £450 million since becoming manager in 2016, but indicated that more would be needed.
"In this competition the teams are so equal and the influence of refereeing decisions is so important", said the Spaniard afterward, denying he had insulted the referee.