Directed by the Russo brothers, Avengers: Infinity War is the most ambitious amassing of superheroes ever on the big screen and comes as Marvel Studios - led by Kevin Feige - celebrates its tenth anniversary.
Final numbers are expected Monday. That would give Infinity War the second largest domestic debut in cinematic history.
Infinity War set records for the highest opening ever in Brazil, South Korea, and Germany. It now stands as the fourth highest preview total in history after Star Wars: The Force Awakens, Star Wars: The Last Jedi, and Harry Potter and the Deathly Hallows - Part 2.
"Super proud of our team who helped on the aerial unit for "Avengers: Infinity War" in The Philippines", the production company said.
Infinity War's opening weekend bests the previous record of $247.9 million set by Star Wars: The Force Awakens back in December 2015 by just over $2 million, but it's also worth mentioning Disney under-estimated Black Panther's $202 million opening by almost $10 million on Sunday.
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' Avengers: Infinity War' established itself as a bona fide victor at the Indian box-office right off the bat when it grossed the highest opening day collection on Friday.
An image released by Marvel Studios shows, front row from left, Danai Gurira, Chadwick Boseman, Chris Evans, Scarlet Johansson and Sebastian Stan in a scene from "Avengers: Infinity War'". That film opened to $248 million in sales in its opening weekend in December 2015. "Fate" still holds the record for global (worldwide total minus US domestic) with $443.2.
According to the states recorded by the Indian Box Office number states the movie has become the Box office blockbuster with collections ranging to around Rs 30.75 crore net on day 1.
Disney is being more cautious and suggesting a domestic launch in the $225 million-$240 million range.
Falling to No. 2 this week is "A Quiet Place", bringing in an estimated $10.6 million in its fourth week out. The film's current worldwide total sits at $284 million worldwide.