Citing law enforcement sources, TMZ says that Demi was transported from a property in the Hollywood Hills to hospital just before noon on Tuesday.
Simply Complicated, Lovato revealed that the last night she drank alcohol - in March 2012 - she was so hungover the next day that she nearly couldn't sing for a scheduled performance on American Idol.
This past March, the 25-year-old celebrated six years of sobriety, sharing the news on Instagram and Twitter, but a few months later she released the piano ballad "Sorry", which alluded to her relapse in its heartbreaking lyrics.
In her June song "Sober", she sings "Momma, I'm so sorry, I'm not sober anymore".
"We should all wrap our arms of love around Demi Lovato", tweeted Gaga.
In the 2017 YouTube documentary, "Simply Complicated", she talked about the daily challenges of recovery.
She even gave interviews about her new sober lifestyle while high on drugs she said, while cycling through sober companions.
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Representatives for Lovato did not respond to a request for comment.
Australian actress Ruby Rose sent a powerful note of support, telling the "Sober" singer she was strong enough to "fight this".
Lovato has been outspoken about her battle with addiction, eating disorders and mental illness.
Demi is now mid-way through her world tour and was next due to perform on Thursday in Atlantic City, but the performance has been cancelled. "Our thoughts go out to Demi and her family", the statement read.
Singer Demi Lovato performs at the 2016 Global Citizen Festival in Central Park to end extreme poverty by 2030 at Central Park on September 24, 2016 in New York City. "We wanted to see Demi".